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Medical Emergencies · single question

All of the following characterize type 1 diabetes mellitus EXCEPT:

  1. Peripheral insulin resistance as the primary defect
  2. Autoimmune destruction of pancreatic beta-cells
  3. Absolute insulin deficiency
  4. A tendency toward diabetic ketoacidosis
Show answer and explanation

Correct answer: A. Peripheral insulin resistance as the primary defect

  • A. Correct (the EXCEPTION). Insulin resistance is the hallmark of TYPE 2 diabetes. Type 1 is an absolute insulin deficiency, not a resistance problem.
  • B. Incorrect. Type 1 results from autoimmune beta-cell destruction.
  • C. Incorrect. The beta-cell loss produces an absolute lack of insulin.
  • D. Incorrect. Without insulin, type 1 patients are prone to ketoacidosis.

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