Pharmacology · single question

Albuterol (ProAir®) can cause each of the following EXCEPT:

  1. Tachycardia
  2. Inhibition of histamine release from mast cells
  3. Increased salivary secretion
  4. Relaxation of bronchial smooth muscle
Show answer and explanation

Correct answer: C. Increased salivary secretion

  • A. Incorrect — this IS an effect. Albuterol (β2-agonist) relaxes bronchial smooth muscle — its primary therapeutic action.
  • B. Incorrect — this IS an effect. Albuterol inhibits histamine release from mast cells via β2-receptor stimulation.
  • C. Correct — this is the EXCEPTION. Albuterol does NOT increase salivary secretion. As a sympathomimetic it causes xerostomia (dry mouth) by inhibiting parasympathetic salivary function.
  • D. Incorrect — this IS an effect. Albuterol causes tachycardia through β1 cross-reactivity and reflex mechanisms.

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