Infection Control · single question
After a needlestick injury, what is the recommended window for initiating post-exposure prophylaxis?
Show answer and explanation
Correct answer: C. Within 0-24 hours (as soon as possible)
- A. Every bloodborne pathogen exposure is urgent, not only HIV.
- B. Seven days is well past the window of maximum efficacy.
- C. Correct. PEP is most effective the sooner it starts — ideally within hours. For HIV the target is under 2 hours and no later than 72 hours; hepatitis B immunoglobulin/vaccine should be given within 24 hours.
- D. Thirty days is far too late for effective prophylaxis.
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