Medical Emergencies · single question

A patient's medical history lists losartan and metformin. Which combination of medical conditions does this patient MOST LIKELY have?

  1. COPD + Osteoporosis
  2. Heart failure + Type 1 diabetes mellitus
  3. Hypertension + Type 2 diabetes mellitus
  4. Atrial fibrillation + Hypothyroidism
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Correct answer: C. Hypertension + Type 2 diabetes mellitus

  • A. COPD uses bronchodilators (albuterol, tiotropium) and osteoporosis uses bisphosphonates or denosumab — neither losartan nor metformin.
  • B. Heart failure uses ACE inhibitors, ARBs, beta-blockers, and diuretics. Type 1 diabetes requires INSULIN, not metformin. Metformin is specifically for Type 2 diabetes.
  • C. CORRECT. Losartan is an angiotensin II receptor blocker (ARB) used for HYPERTENSION (and diabetic nephropathy). Metformin is a biguanide used as first-line oral medication for TYPE 2 DIABETES. Together, these two medications indicate the patient has both hypertension AND type 2 diabetes — a common comorbid combination.
  • D. Atrial fibrillation requires rate control (beta-blockers, CCBs) or rhythm control ± anticoagulation — not losartan primarily. Losartan is an antihypertensive/ARB.

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