Periodontics · single question

A patient with periodontitis is allergic to tetracyclines. What is the BEST alternative local delivery antimicrobial treatment?

  1. Systemic minocycline
  2. Systemic doxycycline
  3. Chlorhexidine chip (microchip)
  4. Systemic azithromycin
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Correct answer: C. Chlorhexidine chip (microchip)

C) Chlorhexidine chip — CORRECT.
If a patient is allergic to tetracyclines (which include doxycycline and minocycline — both used in periodontal local delivery), the appropriate LOCAL delivery antimicrobial alternative is the CHLORHEXIDINE CHIP (PerioChip). It releases chlorhexidine gluconate into periodontal pockets over 7–10 days and is not a tetracycline — safe for tetracycline-allergic patients.
A) Minocycline: A TETRACYCLINE (semi-synthetic) — contraindicated in tetracycline allergy.
B) Doxycycline: A TETRACYCLINE — also contraindicated in tetracycline-allergic patients.
D) Systemic azithromycin: A macrolide — safe in tetracycline allergy, but not a local delivery device. The question asks about local delivery antimicrobial treatment.

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