Pathology · single question
A patient presents with unilateral vesicular lesions on the hard palate. What is the diagnosis?
Show answer and explanation
Correct answer: A. Varicella-Zoster Virus (VZV) / Herpes Zoster
✓ A) VZV/Herpes Zoster is correct.
Herpes Zoster (shingles — reactivation of VZV) causes unilateral vesicular eruptions that follow a dermatomal distribution. Intraorally, it can affect one side of the hard palate and gingiva following the distribution of CN V branches. The unilateral presentation is characteristic. Primary VZV (chickenpox) is generalized. Primary HSV causes widespread bilateral ulcers. Candidiasis appears as white plaques (pseudomembranous) or erythematous areas, not vesicles.
Herpes Zoster (shingles — reactivation of VZV) causes unilateral vesicular eruptions that follow a dermatomal distribution. Intraorally, it can affect one side of the hard palate and gingiva following the distribution of CN V branches. The unilateral presentation is characteristic. Primary VZV (chickenpox) is generalized. Primary HSV causes widespread bilateral ulcers. Candidiasis appears as white plaques (pseudomembranous) or erythematous areas, not vesicles.