Anatomy & Histology · single question
A patient presents with facial drooping on one side but is able to close the eye on the affected side. Which cranial nerve is most likely involved?
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Correct answer: B. CN VII (Facial nerve) — central (supranuclear) lesion
This presentation is key to differentiating central from peripheral facial nerve lesions. The forehead and eye-closing muscles (orbicularis oculi) receive bilateral cortical input — both cerebral hemispheres innervate the upper face bilaterally. In a CENTRAL (supranuclear/upper motor neuron) CN VII lesion (e.g., stroke), the upper face is spared because the contralateral hemisphere compensates. The result: the patient can still close their eye (upper face preserved) but has contralateral lower face weakness (droop). In a PERIPHERAL (lower motor neuron/Bell's palsy) CN VII lesion, ALL ipsilateral facial muscles are affected — the patient CANNOT close the eye. The ability to close the eye indicates a central lesion, not peripheral.
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