Pathology · single question

A patient presents with a small bony protuberance on the buccal surface of the maxillary anterior region. A biopsy is taken. What would the histologic finding show?

  1. Granulation tissue and inflammatory infiltrate
  2. Giant cells in a fibrous stroma
  3. Fibrous connective tissue replacing bone
  4. Normal mucosa overlying normal lamellar bone
Show answer and explanation

Correct answer: D. Normal mucosa overlying normal lamellar bone

  • A. Granulation tissue and inflammation suggest pathology — exostosis is a normal anatomic variant.
  • B. Giant cells in fibrous stroma describes a central giant cell granuloma or giant cell tumor.
  • C. Fibrous connective tissue replacing bone describes fibrous dysplasia or chronic osteomyelitis.
  • D. Correct. An exostosis is a benign bony outgrowth covered by normal mucosa. Biopsy shows normal surface mucosa overlying normal lamellar (compact) bone — no pathologic changes. This distinguishes it from fibrous dysplasia or giant cell lesions.

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