Pathology · single question

A patient on amlodipine presents with generalized gingival overgrowth. The most likely cause is:

  1. Medication-induced (calcium channel blocker)
  2. Poor oral hygiene alone
  3. Hormonal change
  4. Leukemic infiltration
Show answer and explanation

Correct answer: A. Medication-induced (calcium channel blocker)

  • A. Correct. Amlodipine is a calcium channel blocker — one of the three classic drug classes (with phenytoin and cyclosporine) causing gingival enlargement.
  • B. Plaque worsens drug-induced overgrowth but is not the primary cause here.
  • C. Hormonal overgrowth (e.g., pregnancy) doesn't fit a patient on amlodipine.
  • D. Leukemic enlargement is possible but far less likely than the obvious CCB association.

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