Radiology · single question

A patient is diagnosed with multiple myeloma. What is the name of the radiographic pattern?

  1. Punched out
  2. “Cotton wool”
  3. “Soap bubble”
  4. Salt and pepper
Show answer and explanation

Correct answer: A. Punched out

  • A. Correct. Multiple myeloma classically produces multiple well-defined 'punched-out' radiolucencies (lytic lesions), often in the skull and jaws.
  • B. 'Cotton wool' opacities are seen in Paget disease of bone.
  • C. 'Soap bubble' multilocular radiolucencies are associated with ameloblastoma and odontogenic keratocysts.
  • D. 'Salt and pepper' skull appearance is associated with hyperparathyroidism.

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