Medical Emergencies · single question

A patient has rheumatoid arthritis treated with immunosuppressive/biologic therapy. A key complication of this treatment is:

  1. Increased risk of infection
  2. Myocardial infarction
  3. Hyperthyroidism
  4. Polycythemia
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Correct answer: A. Increased risk of infection

  • A. Correct. Methotrexate and TNF-alpha inhibitors (e.g., adalimumab) suppress immunity, increasing susceptibility to infection.
  • B. MI is not a primary expected complication of RA immunosuppressants.
  • C. These drugs do not cause hyperthyroidism.
  • D. They tend to cause cytopenias (e.g., from methotrexate), not polycythemia.

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