Anesthesia · single question

A mother asks how to reduce prolonged effects of local anesthesia in her child after a procedure. Which of the following would NOT help avoid prolonged anesthetic effects?

  1. OraVerse (phentolamine mesylate) reversal agent
  2. Advising the child not to bite the numb lip
  3. Naloxone reversal
  4. Using shorter-acting anesthetics
Show answer and explanation

Correct answer: C. Naloxone reversal

C) Naloxone — CORRECT (does NOT reverse local anesthesia).
Naloxone (Narcan) is an opioid receptor ANTAGONIST — it reverses opioid toxicity. It has absolutely no effect on local anesthetics (sodium channel blockers). It cannot and does not reverse local anesthetic effects.
A) OraVerse (phentolamine mesylate): An alpha-adrenergic blocker that increases blood flow at the injection site, accelerating local anesthetic clearance. Approved for reversing soft tissue anesthesia in children.
B) Advising against biting: Appropriate safety instruction to prevent self-inflicted soft tissue injury while numb.
D) Shorter-acting anesthetics: Using mepivacaine without vasoconstrictor gives shorter duration — a valid strategy.

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