Pathology · single question

A healthy, stressed patient presents with clusters of vesicles on the hard palate. The most appropriate treatment is:

  1. Corticosteroids
  2. Antiviral (acyclovir)
  3. Observation only (lesions are self-limiting)
  4. Antibiotics
Show answer and explanation

Correct answer: B. Antiviral (acyclovir)

  • A. Corticosteroids are used for aphthous ulcers, lichen planus, and autoimmune conditions — they are contraindicated in active viral infections as they can worsen the infection.
  • B. Correct. Clusters of vesicles on the hard palate in a stressed but otherwise healthy patient are characteristic of recurrent intraoral herpes simplex (HSV-1 reactivation). Antiviral therapy (acyclovir, valacyclovir) reduces duration and severity.
  • C. While recurrent herpes is self-limiting (7–10 days), treatment with antivirals accelerates healing and is the recommended clinical approach.
  • D. Herpetic lesions are viral; antibiotics have no effect on HSV infections.

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