Pharmacology · single question

A 56-year-old female with hypertension, hyperlipidemia, and asthma takes Albuterol, Atorvastatin, and Metoprolol. What is the mechanism of action of the medication controlling her HYPERTENSION?

  1. Competitively inhibits β2 adrenergic receptors
  2. Competitively inhibits β1 adrenergic receptors
  3. Blocks calcium channels
  4. Increases nitric oxide release
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Correct answer: A. Competitively inhibits β2 adrenergic receptors

  • A. Correct. Metoprolol (Lopressor) controls hypertension. It is a cardioselective β1-blocker that reduces heart rate and cardiac output.
  • B. Incorrect. Nitric oxide release is the MOA of nitroglycerin/nitrates.
  • C. Incorrect. Calcium channel blockade is amlodipine/verapamil.
  • D. Incorrect. Metoprolol is β1-selective. Albuterol is the β2 agonist in this patient (for asthma).

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