Pathology · single question

A 35-year-old female has a two-year history of a migratory, irregular erythematous lesion on her tongue that changes position over time. She reports discomfort when eating spicy food or cold beverages. The clinical diagnosis is erythema migrans (geographic tongue / benign migratory glossitis). What is the most appropriate treatment for symptomatic cases?

  1. Topical triamcinolone acetonide 0.1% paste
  2. Systemic antifungal therapy (fluconazole)
  3. Incisional biopsy to rule out malignancy
  4. Antiviral therapy (acyclovir)
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Correct answer: A. Topical triamcinolone acetonide 0.1% paste

Erythema migrans (geographic tongue / benign migratory glossitis) is a benign, inflammatory condition characterized by irregular erythematous patches that migrate across the tongue dorsum. Most cases are asymptomatic and require only reassurance. For SYMPTOMATIC cases (burning, sensitivity to spicy or acidic foods), topical corticosteroids — particularly triamcinolone acetonide 0.1% — are the most evidence-based first-line treatment. Multiple clinical trials confirm triamcinolone reduces the burning sensation and lesion size. Biopsy is NOT indicated as the appearance is pathognomonic. Antifungal or antiviral therapy are not appropriate; this condition is neither fungal nor viral in origin. Patients should avoid triggering foods and be reassured the condition is benign and self-limiting, though it may recur.

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