Pharmacology · single question

A 28-year-old in her third trimester has dental pain. Which analgesic should generally be avoided in the third trimester?

  1. Acetaminophen
  2. Ibuprofen
  3. Lidocaine (without epinephrine)
  4. Local anesthetic with epinephrine in minimal dose
Show answer and explanation

Correct answer: B. Ibuprofen

  • A. INCORRECT. Acetaminophen is the preferred analgesic in pregnancy.
  • B. CORRECT. NSAIDs such as ibuprofen are avoided in the third trimester because they can cause premature closure of the ductus arteriosus and other fetal risks.
  • C. INCORRECT. Lidocaine is acceptable for needed dental anesthesia.
  • D. INCORRECT. Minimal-dose epinephrine with local anesthetic is generally acceptable when needed.

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