Start practicing

Medical Emergencies · single question

A 27-year-old carries Factor V Leiden. Which statement about this condition is NOT true?

  1. It is the most common inherited thrombophilia
  2. It causes resistance to activated protein C
  3. Oral contraceptive use reduces the risk of clot formation
  4. It increases the risk of deep vein thrombosis
Show answer and explanation

Correct answer: C. Oral contraceptive use reduces the risk of clot formation

  • A. True — Factor V Leiden is the most common inherited hypercoagulable state, present in roughly 5% of people of European descent.
  • B. True — the mutation makes factor Va resistant to cleavage by activated protein C, so it persists and drives thrombin generation.
  • C. Correct as the false statement. Estrogen-containing contraceptives markedly INCREASE thrombotic risk in Factor V Leiden carriers — the combination raises DVT risk substantially over either factor alone.
  • D. True — venous thromboembolism is the principal clinical consequence.

Practice Medical Emergencies questions Medical Emergencies study notes

More Medical Emergencies practice questions