Pathology · single question

A 17-year-old boy comes with his parents complaining of a lesion on the palate. He has been under stress recently but is otherwise healthy with no systemic symptoms. What is the most likely diagnosis?

  1. Aphthous ulcer
  2. Primary herpes (Herpetic Gingivostomatitis)
  3. Recurrent herpes (Herpes Labialis/Intraoral)
  4. Varicella-Zoster (VZV)
Show answer and explanation

Correct answer: C. Recurrent herpes (Herpes Labialis/Intraoral)

✓ C) Recurrent herpes is correct.
Recurrent intraoral herpes simplex (type 1) typically occurs on KERATINIZED tissue — hard palate, attached gingiva — and is triggered by stress, sunlight, immunosuppression. The patient is older (17), suggesting a recurrence (primary HSV usually occurs in younger children with systemic symptoms). Primary herpes causes widespread ulcers with fever/lymphadenopathy. Aphthous ulcers occur on NON-keratinized mucosa. VZV would cause unilateral dermatomal distribution.

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