Medical Emergencies · patient case with 2 questions
Two chronic conditions and a set of labs
Patient: Male, 47 years old
Chief Complaint: Presents for extraction of a non-restorable molar.
Background: HIV diagnosed nine years ago, on antiretroviral therapy. Type 2 diabetes for six years, on metformin. BMI 34.
Laboratory: CD4+ count 302 cells/µL · HbA1c 9.0% · Viral load undetectable
Vital Signs: BP 138/86 mmHg · HR 80 bpm
Question 1
Which laboratory finding is most significant for the management of this extraction?
Show answer and explanation
Correct answer: B. The HbA1c of 9.0%, indicating poorly controlled diabetes
- A. Severe immunosuppression begins below 200. There is no basis to defer treatment on immunological grounds here.
- B. CORRECT. A CD4 count of 302 is ABOVE the 200 cells/µL threshold and the viral load is undetectable — this patient's HIV is well controlled and routine dental care proceeds without modification. The HbA1c of 9.0% is the number that actually changes management: it reflects an average glucose around 212 mg/dL over the preceding two to three months, meaning impaired neutrophil function, delayed wound healing and a raised risk of post-extraction infection.
- C. AIDS is defined by a CD4 count BELOW 200 cells/µL, or by the presence of an AIDS-defining illness. At 302 with an undetectable viral load, this patient does not meet that definition.
- D. An undetectable viral load is the goal of therapy and reassuring. It is not an indication for prophylaxis; HIV status alone never is.
Question 2
Which statement about type 2 diabetes is correct?
Show answer and explanation
Correct answer: C. The majority of people with the condition are overweight or obese
- A. Type 2 is managed first with lifestyle change and oral agents such as metformin. Insulin may be added later as beta-cell function declines, but it is not required at diagnosis.
- B. Autoimmune destruction of beta cells defines TYPE 1 diabetes, with anti-GAD and islet-cell antibodies.
- C. CORRECT. Excess adiposity, particularly visceral fat, is the dominant modifiable risk factor for type 2 diabetes — the large majority of patients are overweight or obese at diagnosis, and adipose-driven insulin resistance is the central mechanism. This patient's BMI of 34 fits the pattern. Weight loss can meaningfully improve or even remit early type 2 diabetes.
- D. Childhood onset with ketoacidosis is the classic type 1 presentation. Type 2 usually presents in adulthood and is often found on screening in an asymptomatic patient.