Biostatistics & Research · patient case with 3 questions

Evidence, vital signs and dental age

Scenario: Three items in research methods, medicine and growth.

Question 1

Which study design provides the highest level of evidence among those listed?

  1. Case series
  2. Cohort study
  3. Randomised controlled trial
  4. Case-control study
Show answer and explanation

Correct answer: C. Randomised controlled trial

  • A. A case series simply describes a group of patients with no comparison group at all — near the bottom of the hierarchy.
  • B. A cohort study follows exposed and unexposed groups forward and yields relative risk and incidence, but without randomisation confounding remains.
  • C. Correct. Randomisation distributes known and unknown confounders evenly between groups, so the RCT gives the strongest causal inference of the designs listed.
  • D. Case-control studies work backward from outcome to exposure. They are efficient for rare diseases but give odds ratios and are prone to recall bias.

Note: When a systematic review or meta-analysis appears among the options, it outranks the individual RCT. Here it was not offered.

Permanent page for this question

Question 2

A blood pressure of 132/85 mmHg falls into which category?

  1. Hypertensive crisis
  2. Elevated blood pressure
  3. Stage 2 hypertension
  4. Stage 1 hypertension
Show answer and explanation

Correct answer: D. Stage 1 hypertension

  • A. Hypertensive crisis is above 180 systolic or above 120 diastolic and calls for immediate medical attention.
  • B. Elevated blood pressure requires systolic 120-129 AND diastolic below 80. A diastolic of 85 rules that out, and 132 systolic is above the range regardless.
  • C. Stage 2 begins at 140 systolic or 90 diastolic.
  • D. Correct. Under the 2017 ACC/AHA guideline, stage 1 hypertension is a systolic of 130-139 OR a diastolic of 80-89. This reading meets both criteria.

Note: That is incorrect. The reference table written in the margin of the same file actually contradicts the marked answer — 132/85 is stage 1 by both the systolic and the diastolic criterion. Worth correcting in the group notes.

Permanent page for this question

Question 3

A 5-year-old already has erupted permanent mandibular incisors. Which statement about the chronological age is correct?

  1. The chronological age is behind the dental age
  2. Dental age cannot be assessed from eruption
  3. The chronological age is ahead of the dental age
  4. Chronological and dental age match
Show answer and explanation

Correct answer: A. The chronological age is behind the dental age

  • A. Correct. Permanent mandibular incisors normally erupt around 6-7 years. Eruption at 5 means development has run ahead of the calendar, so dental age exceeds chronological age — the child's chronological age lags behind.
  • B. Eruption timing is one of the standard methods of estimating dental age, alongside calcification staging, which is actually the more reliable of the two.
  • C. This reverses the relationship. If the calendar were ahead of development, the teeth would be late, not early.
  • D. They do not match here; that is the whole point of the item.

Note: ⚑ Read this stem carefully — the wording asks about the chronological age relative to the dental age, which inverts the intuitive answer. Several group members reported keying it the other way.

Permanent page for this question

Practice patient cases Biostatistics & Research study notes